2025 Intracranial Hypotension Conference

2025 Intracranial Hypotension Conference

Hosted by Cedars-Sinai, Duke University, University of Freiburg, and University of Amsterdam
Date: June 28-29, 2025
Location: Amsterdam, The Netherlands, and virtual
Course Co-directors: Jürgen Beck, MD, Matthijs Brouwer, MD, PhD, Peter G. Kranz, MD, Wouter I. Schievink, MD

This two-day symposium brought together international experts from around the world to discuss the latest advances in the diagnosis and management of Spontaneous Intracranial Hypotension (SIH) and related CSF leak disorders. The program covered a wide range of topics, including clinical presentation, diagnostic techniques, treatment modalities, controversies in management, and international cooperation in SIH research and treatment. The Spinal CSF Leak Foundation supported this conference with an educational grant.

Each of the following images from the the 2025 Intracranial Hypotension Conference links out to a separate page with the talk video and associated transcript. Most talks also have accompanying slides uploaded to our website as well. We hope that these video replays help further our mission of education, advocacy, and raising awareness for all people suffering from intracranial hypotension or spinal CSF leak.

Introduction to Spontaneous Intracranial Hypotension

Clinical Spectrum of SIH — Dr. Matthijs Brouwer
The Multidimensional Impact of SIH — Dr. Manjit Matharu
Anatomy of Spontaneous Spinal CSF Leaks — Dr. Jürgen Beck

How I Do It (With Diagnostic Algorithms)

How I Do It: Epidural Blood Patching — Dr. Horst Urbach
How I Do It: Percutaneous Fibrin Sealant — Dr. Lalani Carlton Jones
How I Do It: Endovascular Embolization — Dr. Marcel Maya
How I Do It: Surgical Repair — Dr. Wouter Schievink

What to Do?

What To Do? Persistent Headache After CSF Leak Resolution — Dr. Katharina Wolf
What To Do? Brain MRI + SIH Without Detectable Spinal CSF Leak — Dr. Wouter Schievink
What To Do? Dural Ectasia and Orthostatic Headaches — Dr. Marcus Stoodley
What To Do? Orthostatic Headache with Normal Imaging — Dr. Deborah Friedman

Long Term Sequelae of SIH vs Other Conditions

Syringomyelia: Chiari vs SIH — Dr. Marcus Stoodley
Spinal Cord Herniation: Idiopathic vs SIH — Dr. Hans Amelink
Superficial Siderosis: Cerebral Amyloid Angiopathy vs SIH — Dr. Jürgen Beck

Controversies In Spontaneous Intracranial Hypotension

Controversies in SIH: Dynamic CT Myelography by Dr. Lalani Carlton Jones vs DSM by Dr. Marcel Maya
Controversies in SIH: Non-Directed Epidural Blood Patch by Dr. Levi Chazen vs Directed Treatment by Dr. Timothy Amrhein
Controversies in SIH: Surgical Ligation by Dr. Jürgen Beck vs Endovascular Embolization by Dr. Thien Huynh vs Percutaneous Fibrin Sealant by Dr. Mark Mamlouk
Controversies in SIH: To Treat Without Confirmation by Dr. Ian Carroll vs With Confirmation of a Leak by Dr. Wouter Schievink

International Cooperation for Spontaneous Intracranial Hypotension

Introducing the International Society for Spinal CSF Leak (ISSCL) — Dr. Peter Kranz

Post-Dural Puncture Headache

The Origins of PDPH — Dr. Alexandra Schyns Van Den Berg
Prevention of PDPH — Dr. Lisa Leffert
Percutaneous Treatment of PDPH (Including 360° Patching) — Dr. Timothy Amrhein
Surgical Treatment of PDPH — Dr. Jürgen Beck

Skull Base CSF Leaks

Physiology of Skull Base Leaks vs Spinal CSF Leaks — Dr. Peter Kranz
Glymphatics in SIH — Dr. Horst Urbach
Prevention of Skull Base CSF Leaks — Dr. John Yu
Treatment of Skull Base CSF Leaks — Dr. Ray Chu

Pressing issues in SIH & Poster Abstracts

Pressing Issues in SIH — Dr. Andrew Callen
Poster Abstract: Predictive Value Of Negative Brain Or Low Probability Brain MRIs In Patients With CVFs — Dr. Angelique Sao-Mai Tay
Poster Abstract: Endoscopic Sealing of Ventral Dural Defect with Transforaminal Approach: A Novel Methods and Outcomes — Dr. Mi Ji Lee

Q&A Sessions

2025 Intracranial Hypotension Conference – Q&A 1 – How I Do It
2025 Intracranial Hypotension Conference – Q&A 2 – What To Do + Long Term Sequelae of SIHSI
2025 Intracranial Hypotension Conference – Q&A 3 – Controversies in SIH
2025 Intracranial Hypotension Conference – Q&A 4 – PDPH and Skull Base CSF Leaks